Kirsten Tolstrup, MD

Professor

Cardiology UCSF Health

Clinical Interests:

Kirsten Tolstrup is a non-invasive cardiologist with special interest in echocardiography, valvular and structural heart disease. Her clinical interests include use of transthoracic echocardiography, transesophageal and three-dimensional transesophageal echocardiography and supine bicycle stress testing with echocardiography for the evaluation of cardiovascular disease in general and valvular heart disease in particular. Dr. Tolstrup works closely with the interventional team on transcatheter based procedures such as TAVR and MitraClip.

Academic Interests:

Dr. Tolstrup’s focus is on implementation of new noninvasive procedures and development of multidisciplinary team approach to cardiovascular care. Her research interests are primarily centered around valvular heart disease and echocardiography as they relate to clinical aspects.

Education
06/2001 - Cardiovascular Medicine, UNM Health Sciences Center
06/1998 - Internal Medicine, USC-LAC Medical Center
09/1994 - Internal Medicine, Surgery and Family Practice, Hospitals Region Syd
MD, 01/1993 - Medicine, Copenhagen Health Sciences
Publications
  1. Mital R, Ramakrishna S, Judson GL, Watt C, Tolstrup K, Mahadevan VS. Transcatheter Edge-to-Edge Repair for Left Atrioventricular Valve Cleft After Previously Repaired Complete Atrioventricular Canal Defect in Down Syndrome. CASE (Philadelphia, Pa.) 2022. PMID: 36704485


  2. Rowan CJ, Eskander MA, Seabright E, Rodriguez DE, Linares EC, Gutierrez RQ, Adrian JC, Cummings D, Beheim B, Tolstrup K, Achrekar A, Kraft T, Michalik DE, Miyamoto MI, Allam AH, Wann LS, Narula J, Trumble BC, Stieglitz J, Thompson RC, Thomas GS, Kaplan HS, Gurven MD. Very Low Prevalence and Incidence of Atrial Fibrillation among Bolivian Forager-Farmers. Annals of global health 2021. PMID: 33633929


  3. Parikh DS, Blissett S, Tolstrup K, Mahadevan VS. A Complex Tricuspid Clip: Bridging the Decision. JACC. Case reports 2020. PMID: 34317421


  4. Lassen MCH, Olsen FJ, Skaarup KG, Tolstrup K, Qasim AN, Gislason G, Biering-Sørensen T. The clinical application of the ratio of transmitral early filling velocity to early diastolic strain rate: a systematic review and meta-analysis. Journal of echocardiography 2020. PMID: 32189214


  5. Wang TS, Bergsland EK, Zhang R, Ihnken K, Tolstrup K. A Rare Case of Carcinoid Constrictive Pericarditis. JACC. Case reports 2020. PMID: 34316954


  6. Gerstein NS, Clegg SD, Levin DB, Fish AC, Tolstrup K, Nakanishi K, Yoshida Y, Homma S. A Case-Based Discussion on the Management of Cryptogenic Stroke and Patent Foramen Ovale in the Patient With a Hypercoagulable Disorder. Journal of cardiothoracic and vascular anesthesia 2019. PMID: 31473116


  7. Lassen MCH, Biering-Sørensen SR, Olsen FJ, Skaarup KG, Tolstrup K, Qasim AN, Møgelvang R, Jensen JS, Biering-Sørensen T. Ratio of transmitral early filling velocity to early diastolic strain rate predicts long-term risk of cardiovascular morbidity and mortality in the general population. European heart journal 2018. PMID: 29659790


  8. Saric M, Armour AC, Arnaout MS, Chaudhry FA, Grimm RA, Kronzon I, Landeck BF, Maganti K, Michelena HI, Tolstrup K. Guidelines for the Use of Echocardiography in the Evaluation of a Cardiac Source of Embolism. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2016. PMID: 26765302


  9. Roldan CA, Schevchuck O, Tolstrup K, Roldan PC, Macias L, Qualls CR, Greene ER, Hayek R, Charlton GA, Sibbitt WL. Lambl's Excrescences: Association with Cerebrovascular Disease and Pathogenesis. Cerebrovascular diseases (Basel, Switzerland) 2015. PMID: 26044080


  10. Roldan CA, Tolstrup K, Macias L, Qualls CR, Maynard D, Charlton G, Sibbitt WL. Libman-Sacks Endocarditis: Detection, Characterization, and Clinical Correlates by Three-Dimensional Transesophageal Echocardiography. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2015. PMID: 25807885


  11. Tanaka J, Izumo M, Fukuoka Y, Saitoh T, Harada K, Harada K, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of two-dimensional versus real-time three-dimensional transesophageal echocardiography for evaluation of patent foramen ovale morphology. The American journal of cardiology 2013. PMID: 23352264


  12. Izumo M, Shiota M, Saitoh T, Kuwahara E, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Non-circular shape of right ventricular outflow tract: a real-time 3-dimensional transesophageal echocardiography study. Circulation. Cardiovascular imaging 2012. PMID: 22891043


  13. Saitoh T, Izumo M, Furugen A, Tanaka J, Miyata-Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Kar S, Shiota T. Echocardiographic evaluation of iatrogenic atrial septal defect after catheter-based mitral valve clip insertion. The American journal of cardiology 2012. PMID: 22475361


  14. Saitoh T, Shiota M, Izumo M, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of left ventricular outflow geometry and aortic valve area in patients with aortic stenosis by 2-dimensional versus 3-dimensional echocardiography. The American journal of cardiology 2012. PMID: 22440128


  15. Miyata-Fukuoka Y, Izumo M, Shimada Y, Kuwahara E, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Left atrial size and function are related to pulmonary hypertension in coronary artery disease. Echocardiography (Mount Kisco, N.Y.) 2012. PMID: 22324451


  16. Nalawadi SS, Tolstrup K, Cuk O, Shiota T, Gurudevan SV, Siegel RJ. Atropine as an adjunct to supine bicycle stress echocardiography: an alternative strategy to achieve target heart rate or rate pressure product. European heart journal cardiovascular Imaging 2012. PMID: 22271103


  17. Tolstrup K, Shiota T, Gurudevan S, Luthringer D, Luo H, Siegel RJ. Left atrial myxomas: correlation of two-dimensional and live three-dimensional transesophageal echocardiography with the clinical and pathologic findings. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2011. PMID: 21367578


  18. Thompson KA, Shiota T, Tolstrup K, Gurudevan SV, Siegel RJ. Utility of three-dimensional transesophageal echocardiography in the diagnosis of valvular perforations. The American journal of cardiology 2011. PMID: 21146695


  19. Gurudevan SV, Shah H, Tolstrup K, Siegel R, Krishnan SC. Septal thrombus in the left atrium: is the left atrial septal pouch the culprit? JACC. Cardiovascular imaging 2010. PMID: 21163458


  20. Nalawadi SS, Siegel RJ, Wolin E, Yu R, Trento A, Shiota T, Tolstrup K, Luthringer D, Gurudevan S. Morphologic features of carcinoid heart disease as assessed by three-dimensional transesophageal echocardiography. Echocardiography (Mount Kisco, N.Y.) 2010. PMID: 21039812


  21. Daneshvar D, Wei J, Tolstrup K, Thomson LE, Shufelt C, Merz CN. Diastolic dysfunction: improved understanding using emerging imaging techniques. American heart journal 2010. PMID: 20826245


  22. Biner S, Rafique A, Rafii F, Tolstrup K, Noorani O, Shiota T, Gurudevan S, Siegel RJ. Reproducibility of proximal isovelocity surface area, vena contracta, and regurgitant jet area for assessment of mitral regurgitation severity. JACC. Cardiovascular imaging 2010. PMID: 20223419


  23. Rafique AM, Biner S, Ray I, Forrester JS, Tolstrup K, Siegel RJ. Meta-analysis of prognostic value of stress testing in patients with asymptomatic severe aortic stenosis. The American journal of cardiology 2009. PMID: 19766766


  24. Biner S, Rafique AM, Ray I, Cuk O, Siegel RJ, Tolstrup K. Aortopathy is prevalent in relatives of bicuspid aortic valve patients. Journal of the American College of Cardiology 2009. PMID: 19520254


  25. Biner S, Rafique AM, Wolak A, Tolstrup K, Siegel RJ. Visual assessment of left ventricular dyssynchrony using tissue synchronization imaging. Cardiology 2009. PMID: 19420936


  26. Naqvi TZ, Rafique AM, Swerdlow C, Verma S, Siegel RJ, Tolstrup K, Kerwin W, Goodman J, Gallik D, Gang E, Peter CT. Predictors of reduction in mitral regurgitation in patients undergoing cardiac resynchronisation treatment. Heart (British Cardiac Society) 2008. PMID: 18467354


  27. Goland S, Trento A, Czer LS, Eshaghian S, Tolstrup K, Naqvi TZ, De Robertis MA, Mirocha J, Iida K, Siegel RJ. Thoracic aortic arteriosclerosis in patients with degenerative aortic stenosis with and without coexisting coronary artery disease. The Annals of thoracic surgery 2008. PMID: 18154793


  28. Atar S, Tolstrup K, Cercek B, Siegel RJ. Chlamydia pneumoniae antibody titers and cardiac calcifications: a cross-sectional serological-echocardiographic correlative study. The Israel Medical Association journal : IMAJ 2007. PMID: 17710782


  29. Goland S, Trento A, Iida K, Czer LS, De Robertis M, Naqvi TZ, Tolstrup K, Akima T, Luo H, Siegel RJ. Assessment of aortic stenosis by three-dimensional echocardiography: an accurate and novel approach. Heart (British Cardiac Society) 2007. PMID: 17488766


  30. Kobal SL, Pollick C, Atar S, Miyamoto T, Aslanian N, Neuman Y, Tolstrup K, Naqvi TZ, Luo H, Macrum B, Siegel RJ. Stress echocardiography in octogenarians: transesophageal atrial pacing is accurate, safe, and well tolerated. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2006. PMID: 16880096


  31. Tolstrup K, Madsen BE, Ruiz JA, Greenwood SD, Camacho J, Siegel RJ, Gertzen HC, Park JW, Smars PA. Non-invasive resting magnetocardiographic imaging for the rapid detection of ischemia in subjects presenting with chest pain. Cardiology 2006. PMID: 16733351


  32. Kobal SL, Trento L, Baharami S, Tolstrup K, Naqvi TZ, Cercek B, Neuman Y, Mirocha J, Kar S, Forrester JS, Siegel RJ. Comparison of effectiveness of hand-carried ultrasound to bedside cardiovascular physical examination. The American journal of cardiology 2005. PMID: 16188532


  33. Neuman Y, Tolstrup K, Blanche C, Luthringer D, Kobal S, Miyamoto T, Luo H, Siegel RJ. Pseudomyxoma originating from the interatrial septum in a heart transplant patient. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2005. PMID: 16003277


  34. Neuman Y, Cercek B, Aragon J, Lee S, Kobal S, Miyamoto T, Luo H, Tolstrup K, Naqvi TZ, Birnbaum Y, Siegel RJ. Comparison of frequency of left ventricular wall motion abnormalities in patients with a first acute myocardial infarction with versus without left ventricular hypertrophy. The American journal of cardiology 2004. PMID: 15374782


  35. Luo H, Chen M, Trento A, Miyamoto T, Kobal SL, Neuman Y, Naqvi TZ, Tolstrup K, Siegel RJ. Usefulness of a hand-carried cardiac ultrasound device for bedside examination of pericardial effusion in patients after cardiac surgery. The American journal of cardiology 2004. PMID: 15276121


  36. Kobal SL, Tolstrup K, Luo H, Neuman Y, Miyamoto T, Mirocha J, Naqvi TZ, Siegel RJ. Usefulness of a hand-carried cardiac ultrasound device to detect clinically significant valvular regurgitation in hospitalized patients. The American journal of cardiology 2004. PMID: 15081463


  37. Chen M, Luo H, Miyamoto T, Atar S, Kobal S, Rahban M, Brasch AV, Makkar R, Neuman Y, Naqvi TZ, Tolstrup K, Siegel RJ. Correlation of echo-Doppler aortic valve regurgitation index with angiographic aortic regurgitation severity. The American journal of cardiology 2003. PMID: 12943896


  38. Tolstrup K, Roldan CA, Qualls CR, Crawford MH. Aortic valve sclerosis, mitral annular calcium, and aortic root sclerosis as markers of atherosclerosis in men. Volume 89 of Issue 9. The American journal of cardiology 2002. PMID: 11988190