Alan Baik, MD
Education
Honors and Awards
- American Heart Association-Harold Amos Medical Faculty Development Program, 2024
- Distinguished Achievement in Science Award, Gladstone Institutes, 2023
- Chan-Zuckerberg Biohub Physician-Scientist Fellow, 2021-2023
- Sarnoff Scholar Career Development Award, 2021-2023
- T32 NIH Institutional Training Grant, 2019-2021
- UCSF Dean's Award in Molecular Medicine, 2014
- Sarnoff Cardiovascular Research Fellowship (2nd Year Fellow), 2012-2013
- Sarnoff Cardiovascular Research Fellowship (1st Year Fellow), 2011-2012
Publications
Yan KL, Lee YJ, Baik AH. Acute radiation-induced pericarditis complicated by polymicrobial infectious pericarditis in a patient with mediastinal sarcoma: a case report. European heart journal. Case reports 2024. PMID: 38405193
Lassen MCH, Arya F, Biering-Sørensen T, Reeh JLT, Melisko ME, Sarwary S, Baik AH, Aras MA, Qasim A. Left atrial strain is reduced following trastuzumab in breast cancer patients. Echocardiography (Mount Kisco, N.Y.) 2024. PMID: 38284677
Chen X, Haribowo AG, Baik AH, Fossati A, Stevenson E, Chen YR, Reyes NS, Peng T, Matthay MA, Traglia M, Pico AR, Jarosz DF, Buchwalter A, Ghaemmaghami S, Swaney DL, Jain IH. In vivo protein turnover rates in varying oxygen tensions nominate MYBBP1A as a mediator of the hyperoxia response. Science advances 2023. PMID: 38064566
Patel K, Hsu KY, Lou K, Soni K, Lee YJ, Mulvey CK, Baik AH. Osimertinib-induced biventricular cardiomyopathy with abnormal cardiac MRI findings: a case report. Cardio-oncology (London, England) 2023. PMID: 37908018
Addison D, Branch M, Baik AH, Fradley MG, Okwuosa T, Reding KW, Simpson KE, Suero-Abreu GA, Yang EH, Yancy CW, American Heart Association Cardio-Oncology Committee of the Council on Clinical Cardiology and Counc. Equity in Cardio-Oncology Care and Research: A Scientific Statement From the American Heart Association. Circulation 2023. PMID: 37377045
Baik AH, Haribowo AG, Chen X, Queliconi BB, Barrios AM, Garg A, Maishan M, Campos AR, Matthay MA, Jain IH. Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes. Molecular cell 2023. PMID: 36893757
Baik AH. Immune checkpoint inhibitors and the cardiovascular system: Reflecting on the past and looking towards the future. Trends in cardiovascular medicine 2022. PMID: 36309121
Baik AH. Hypoxia signaling and oxygen metabolism in cardio-oncology. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022. PMID: 34979102
Lehmann LH, Cautela J, Palaskas N, Baik AH, Meijers WC, Allenbach Y, Alexandre J, Rassaf T, Müller OJ, Aras M, Asnani AH, Deswal A, Laufer-Perl M, Thuny F, Kerneis M, Hayek SS, Ederhy S, Salem JE, Moslehi JJ. Clinical Strategy for the Diagnosis and Treatment of Immune Checkpoint Inhibitor-Associated Myocarditis: A Narrative Review. JAMA cardiology 2021. PMID: 34232253
Baik A, Oluwole OO, Johnson DB, Shah N, Salem JE, Tsai KK, Moslehi JJ. Mechanisms of Cardiovascular Toxicities Associated with Immunotherapies. Volume 128 of Issue 11. 2021. PMID: 33934609
Asnani A, Moslehi JJ, Adhikari BB, Baik AH, Beyer AM, de Boer RA, Ghigo A, Grumbach IM, Jain S, Zhu H, American Heart Association Council on Basic Cardiovascular Sciences; Cardio-Oncology Science Subcomm. Preclinical Models of Cancer Therapy-Associated Cardiovascular Toxicity: A Scientific Statement From the American Heart Association. Volume 129 of Issue 1. 2021. PMID: 33934611
Baik AH, Tsai KK, Oh DY, Aras MA. Mechanisms and clinical manifestations of cardiovascular toxicities associated with immune checkpoint inhibitors. Clinical science (London, England : 1979) 2021. PMID: 33686402
John R Power, Joachim Alexandre, Arrush Choudhary, benay ozbay, Nicolas L Palaskas, Lorenz H Lehmann, Daniel Finke, Jennifer Cautela, Franck Thuny, Yuichi Tamura, Salim S Hayek, Tariq U Azam, Aarti Asnani, Tyler Mehegan, Mandar A Aras, Alan H Baik, Lauren Gilstrap, Michal Laufer-Perl, Dimitri Arangalage, Steven Ewer, Matthew Martini, Joseph Nowatzke, Olusola A Orimoloye, Douglas M Brinkley, Wouter C Meijers, Charlotte Fenioux, Stephane EDERHY, Javid J Moslehi, Joe-elie Salem. Abstract 14843: Electrocardiographic Manifestations of Immune Checkpoint Inhibitor Associated Myocarditis. Circulation 2020. PMID:
Joseph Nowatzke, John R Power, Wouter C Meijers, Olusola Orimoloye, Charlotte Fenioux, Yuichi Tamura, Jennifer Cautela, Lorenz H Lehmann, Daniel Finke, Salim Hayek, Tariq U Azam, Aarti Asnani, Tyler Mehegan, Alison Weppler, Alan H Baik, Mandar A Aras, Anna Narezkina, Dimitri Arangalage, fanny rocher, Gerard Alexandre, Nicolas L Palaskas, Joe-elie Salem, Javid Moslehi. Abstract 15365: Natural History of Immune Checkpoint Inhibitor Associated Myocarditis With Preserved Ejection Fraction. Circulation 2020. PMID:
Baik AH, Jain IH. Turning the Oxygen Dial: Balancing the Highs and Lows. Volume 30 of Issue 7. 2020. PMID: 32386878
Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG. EGLN1 Inhibition and Rerouting of a-Ketoglutarate Suffice for Remote Ischemic Protection. Volume 165 of Issue 2. 2016. PMID: 27058668
Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG. EGLN1 Inhibition and Rerouting of a-Ketoglutarate Suffice for Remote Ischemic Protection. Volume 164 of Issue 5. 2016. PMID: 26919427
Alan Baik, Ben Olenchock, Javid Moslehi, William G. Kaelin. ACUTE HYPOXIA-INDUCIBLE FACTOR EGLN1 INACTIVATION PROTECTS AGAINST ISCHEMIA-REPERFUSION INJURY BY REGULATION OF GLUCOSE OXIDATION AND REACTIVE OXYGEN SPECIES GENERATION. Journal of the American College of Cardiology 2013. PMID:
Stewart FJ, Baik AH, Cavanaugh CM. Genetic subdivision of chemosynthetic endosymbionts of Solemya velum along the Southern New England coast. Volume 75 of Issue 18. 2009. PMID: 19633116