Nisha Parikh, MD

Associate Professor

Clinical Interests: Dr. Parikh is a noninvasive cardiologist. She sees both men and women in her clinical practice, emphasizing primary and secondary cardiovascular disease prevention. She also has an interest in women's cardiovascular diseases across the lifespan; including cardiovascular disease in pregnancy and the post-partum period.

Research Interests: Dr. Parikh is a trained cardiovascular epidemiologist and population scientist. She demonstrated in the Multi-Ethnic Study of Atherosclerosis that the hemodynamic changes of pregnancy may not revert back to normal, may be cumulative across successive pregnancies, and can lead to left ventricular remodeling on cardiac MRI in mid-life. Along with a research team at the Framingham Heart Study, she developed a risk score for incident hypertension and this work was cited in the recent version of the US hypertension guidelines. She has added to the scientific knowledge base demonstrating which specific reproductive factors are predictors of cardiovascular disease using data from the NIH sponsored Women's Health Initiative Study and has leveraged data from the Swedish Population Registers. Her work has been supported by grants from the American Heart Association, the NIH/National Heart Lung and Blood Institute and the UCSF Preterm Birth Initiative.

Other interests: Dr. Parikh has been an active volunteer for the American Heart Association (AHA) for over ten years. She currently serves AHA Leadership Committee of the Epidemiology and Prevention Council (national level).
Education
2018 - Diversity, Equity, and Inclusion Champion Training, University of California
06/2010 - Cardiology, Harvard Beth-Israel Deaconess Medical Center
06/2007 - Cardiovascular Epidemiology, Framingham Heart Study/ Boston University School of Medicine
06/2005 - Internal Medicine Residency, Tufts New England Medical Center
MD, 06/2002 - Medicine, New York Medical College
MPH, 05/1997 - Epidemiology and Biostatistics, UC Berkeley
BA, 05/1995 - Molecular and Cellular Biology- Immunology, UC Berkeley
Publications
  1. Søndergaard MM, Hlatky MA, Stefanick ML, Vittinghoff E, Nah G, Allison M, Gemmill A, Van Horn L, Park K, Salmoirago-Blotcher E, Sattari M, Sealy-Jefferson S, Shadyab AH, Valdiviezo C, Manson JE, Parikh NI. Association of Adverse Pregnancy Outcomes With Risk of Atherosclerotic Cardiovascular Disease in Postmenopausal Women. 2020. PMID: 32936228


  2. Kim C, Slaughter JC, Terry JG, Jacobs DR, Parikh N, Appiah D, Leader B, Moravek MB, Wellons MF. Antimüllerian hormone and F2-isoprostanes in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. 2020. PMID: 32682516


  3. DesJardin JT, Healy MJ, Nah G, Vittinghoff E, Agarwal A, Marcus GM, Velez JMG, Tseng ZH, Parikh NI. Placental Abruption as a Risk Factor for Heart Failure. 2020. PMID: 32718545


  4. Rohlfing AB, Nah G, Ryckman KK, Snyder BD, Kasarek D, Paynter RA, Feuer SK, Jelliffe-Pawlowski L, Parikh NI. Maternal cardiovascular disease risk factors as predictors of preterm birth in California: a case-control study. 2020. PMID: 32499261


  5. Parikh NI, Laria B, Nah G, Singhal M, Vittinghoff E, Vieten C, Stotland N, Coleman-Phox K, Adler N, Albert MA, Epel E. Cardiovascular Disease-Related Pregnancy Complications Are Associated with Increased Maternal Levels and Trajectories of Cardiovascular Disease Biomarkers During and After Pregnancy. 2020. PMID: 31934809


  6. Pantell MS, Baer RJ, Torres JM, Felder JN, Gomez AM, Chambers BD, Dunn J, Parikh NI, Pacheco-Werner T, Rogers EE, Feuer SK, Ryckman KK, Novak NL, Tabb KM, Fuchs J, Rand L, Jelliffe-Pawlowski LL. Associations between unstable housing, obstetric outcomes, and perinatal health care utilization. 2019. PMID: 33345843


  7. Strouse J, Donovan BM, Fatima M, Fernandez-Ruiz R, Baer RJ, Nidey N, Forbess C, Bandoli G, Paynter R, Parikh N, Jeliffe-Pawlowski L, Ryckman KK, Singh N. Impact of autoimmune rheumatic diseases on birth outcomes: a population-based study. 2019. PMID: 31168407


  8. Hall PS, Nah G, Vittinghoff E, Parker DR, Manson JE, Howard BV, Sarto GE, Gass ML, Sealy-Jefferson SM, Salmoirago-Blotcher E, Stefanick ML, Shadyab AH, Van Horn LV, Park K, Parikh NI. Relation of Pregnancy Loss to Risk of Cardiovascular Disease in Parous Postmenopausal Women (From the Women's Health Initiative). 2019. PMID: 30871746


  9. Basile M, Press A, Adia AC, Wang JJ, Herman SW, Lester J, Parikh N, Hajizadeh N. Does Calculated Prognostic Estimation Lead to Different Outcomes Compared With Experience-Based Prognostication in the ICU? A Systematic Review. 2019. PMID: 32166250


  10. Sobhani NC, Schultz H, Kheiwa A, Killion M, Parikh NI, Harris IS, Gonzalez JM, Agarwal A. Contraceptive Choices in the Immediate Postpartum Period in Women With Cardiac Disease. 2019. PMID: 30712772


  11. Cortés YI, Parikh N, Allison MA, Criqui MH, Suder N, Barinas-Mitchell E, Wassel CL. Women's Reproductive History and Pre-Clinical Peripheral Arterial Disease in Late Life: The San Diego Population Study. 2018. PMID: 30508411


  12. Parikh NI, Kapphahn K, Hedlin H, Olgin JE, Allison MA, Magnani JW, Ryckman KR, Waring ME, Perez MV, Howard BV. Effects of reproductive period duration and number of pregnancies on midlife ECG indices: a secondary analysis from the Women's Health Initiative Clinical Trial. 2018. PMID: 30121588


  13. Sardana M, Lessard D, Tsao CW, Parikh NI, Barton BA, Nah G, Thomas RC, Cheng S, Schiller NB, Aragam JR, Mitchell GF, Vaze A, Benjamin EJ, Vasan RS, McManus DD. Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study. 2018. PMID: 29602764


  14. Sardana M, Nah G, Tsao CW, Ogunsua AA, Vittinghoff E, Thomas RC, Cheng S, Vaze A, Aragam JR, Mitchell GF, Benjamin EJ, Vasan RS, Aurigemma GP, Schiller NB, McManus DD, Parikh NI. Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study. 2017. PMID: 28735892


  15. Heidecker B, Spencer RM, Hayes V, Hall S, Parikh N, Stock EO, Redberg R. High Prevalence and Clinical/Sociodemographic Correlates of Miscarriages Among Flight Attendants. Volume 130 of Issue 12. 2017. PMID: 28624541


  16. Hall PS, Nah G, Howard BV, Lewis CE, Allison MA, Sarto GE, Waring ME, Jacobson LT, Manson JE, Klein L, Parikh NI. Reproductive Factors and Incidence of Heart Failure Hospitalization in the Women's Health Initiative. 2017. PMID: 28521890


  17. Parikh NI, Norberg M, Ingelsson E, Cnattingius S, Vasan RS, Domellöf M, Jansson JH, Edstedt Bonamy AK. Association of Pregnancy Complications and Characteristics With Future Risk of Elevated Blood Pressure: The Västerbotten Intervention Program. 2017. PMID: 28137991


  18. LeBlanc ES, Kapphahn K, Hedlin H, Desai M, Parikh NI, Liu S, Parker DR, Anderson M, Aroda V, Sullivan S, Woods NF, Waring ME, Lewis CE, Stefanick M. Reproductive history and risk of type 2 diabetes mellitus in postmenopausal women: findings from the Women's Health Initiative. 2017. PMID: 27465714


  19. Sardana M, Ogunsua AA, Spring M, Shaikh A, Asamoah O, Stokken G, Browning C, Ennis C, Donahue JK, Rosenthal LS, Floyd KC, Aurigemma GP, Parikh NI, McManus DD. Association of Left Atrial Function Index With Late Atrial Fibrillation Recurrence after Catheter Ablation. 2016. PMID: 27569695


  20. Elajami TK, Giuseffi J, Avila MD, Hovnanians N, Mukamal KJ, Parikh N, Welty FK. Parity, coronary heart disease and mortality in the old order Amish. 2016. PMID: 27680773


  21. Parikh NI, Jeppson RP, Berger JS, Eaton CB, Kroenke CH, LeBlanc ES, Lewis CE, Loucks EB, Parker DR, Rillamas-Sun E, Ryckman KK, Waring ME, Schenken RS, Johnson KC, Edstedt-Bonamy AK, Allison MA, Howard BV. Reproductive Risk Factors and Coronary Heart Disease in the Women's Health Initiative Observational Study. 2016. PMID: 27143682


  22. Rodriguez F, Stefanick ML, Greenland P, Soliman EZ, Manson JE, Parikh N, Martin LW, Larson JC, Hlatky M, Nassir R, Cené CW, Rodriguez BL, Albert C, Perez MV. Racial and ethnic differences in atrial fibrillation risk factors and predictors in women: Findings from the Women's Health Initiative. 2016. PMID: 27264222


  23. Chow D, Young R, Valcour N, Kronmal RA, Lum CJ, Parikh NI, Tracy RP, Budoff M, Shikuma CM. HIV and coronary artery calcium score: comparison of the Hawaii Aging with HIV Cardiovascular Study and Multi-Ethnic Study of Atherosclerosis (MESA) cohorts. 2015. PMID: 26038953


  24. Sanghavi M, Kulinski J, Ayers CR, Nelson D, Stewart R, Parikh N, de Lemos JA, Khera A. Association between number of live births and markers of subclinical atherosclerosis: The Dallas Heart Study. 2015. PMID: 25691547


  25. Parikh NI, Aurora MS, Dash R, Shin JJ, Palaniappan L. Assessment of Obesity and Cardiovascular Risk in South Asians 2015. PMID:


  26. Munger AM, Chow DC, Playford MP, Parikh NI, Gangcuangco LM, Nakamoto BK, Kallianpur KJ, Ndhlovu LC, Shikuma CM, Mehta NN. Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens. 2014. PMID: 25416403


  27. Parikh NI, Gerschenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN, Playford MP, Nakamoto BK, Seto TB, Chow DC, Shikuma CM. Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort. 2014. PMID: 25574857


  28. Parker DR, Lu B, Sands-Lincoln M, Kroenke CH, Lee CC, O'Sullivan M, Park HL, Parikh N, Schenken RS, Eaton CB. Risk of cardiovascular disease among postmenopausal women with prior pregnancy loss: the women's health initiative. 2014. PMID: 25024237


  29. Ryckman KK, Rillamas-Sun E, Spracklen CN, Wallace RB, Garcia L, Tylavsky FA, Howard BV, Liu S, Song Y, LeBlanc ES, White MV, Parikh NI, Robinson JG. Ethnic differences in the relationship between birth weight and type 2 diabetes mellitus in postmenopausal women. 2014. PMID: 24751988


  30. Shikuma CM, Chow DC, Gangcuangco LM, Zhang G, Keating SM, Norris PJ, Seto TB, Parikh N, Kallianpur KJ, Nakamoto BK, Nagamine LS, Ndhlovu LC, Barbour JD. Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV. 2014. PMID: 24587328


  31. Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM. Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy. 2013. PMID: 24401216


  32. Nakamoto BK, Shikuma CM, Ogata-Arakaki D, Umaki T, Neuwelt EA, Shiramizu BT, Chow DC, Parikh NI, Kallianpur KJ, Hamilton BE. Feasibility and potential role of ferumoxytol-enhanced neuroimaging in HIV-associated neurocognitive disorder. 2013. PMID: 24129909


  33. Chua Chiaco JM, Parikh NI, Fergusson DJ. The jugular venous pressure revisited. 2013. PMID: 24085809


  34. Jalbert E, Crawford TQ, D'Antoni ML, Keating SM, Norris PJ, Nakamoto BK, Seto T, Parikh NI, Shikuma CM, Ndhlovu LC, Barbour JD. IL-1? enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease. 2013. PMID: 24086545


  35. Shikuma CM, Barbour JD, Ndhlovu LC, Keating SM, Norris PJ, Budoff M, Parikh N, Seto T, Gangcuangco LM, Ogata-Arakaki D, Chow D. Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-a levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors. 2013. PMID: 23984974


  36. Chow D, Nakamoto B, So E, Parikh N, Souza S, Kallianpur K, Shikuma C. Rates of autonomic dysfunction in HIV patients receiving antiretroviral therapy. 2013. PMID: 24018903


  37. Tongma C, Shikuma CM, Nakamoto BK, Kallianpur KJ, Umaki TM, Barbour JD, Ndhlovu L, Parikh NI, Chow DC. Albuminuria as a marker of cardiovascular risk in HIV-infected individuals receiving stable antiretroviral therapy. 2013. PMID: 24052917


  38. Won S, Hong RA, Shohet RV, Seto TB, Parikh NI. Methamphetamine-associated cardiomyopathy. 2013. PMID: 24037954


  39. Ryckman KK, Borowski KS, Parikh NI, Saftlas AF. Pregnancy Complications and the Risk of Metabolic Syndrome for the Offspring. 2013. PMID: 23997844


  40. Edstedt-Bonamy A-K, Parikh NI. Current Cardiovascular Risk Reports. Eds. Robinson JF and Levy D 2013. PMID:


  41. Lin C, Grandinetti A, Shikuma C, Souza S, Parikh N, Nakamoto B, Kallianpur KJ, Chow D. The effects of extended release niacin on lipoprotein sub-particle concentrations in HIV-infected patients. 2013. PMID: 23795312


  42. Carty CL, Spencer KL, Setiawan VW, Fernandez-Rhodes L, Malinowski J, Buyske S, Young A, Jorgensen NW, Cheng I, Carlson CS, Brown-Gentry K, Goodloe R, Park A, Parikh NI, Henderson B, Le Marchand L, Wactawski-Wende J, Fornage M, Matise TC, Hindorff LA, Arnold AM, Haiman CA, Franceschini N, Peters U, Crawford DC. Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study. 2013. PMID: 23508249


  43. Chow D, Kocher M, Shikuma C, Parikh N, Grandinetti A, Nakamoto B, Seto T, Low P. Effects of antiretroviral therapy on autonomic function in early HIV infection: a preliminary report. 2012. PMID: 22859899


  44. Chow D, Thomas BS, Liang CY, Souza SC, Nakamoto BK, Parikh NI, Shikuma C. Role of the veterans aging cohort study index in assessing total atherosclerotic burden. 2012. PMID: 22670040


  45. Parikh NI, Lloyd-Jones DM, Ning H, Ouyang P, Polak JF, Lima JA, Bluemke D, Mittleman MA. Association of number of live births with left ventricular structure and function. The Multi-Ethnic Study of Atherosclerosis (MESA). 2012. PMID: 22424019


  46. Parikh NI, Cnattingius S, Mittleman MA, Ludvigsson JF, Ingelsson E. Subfertility and risk of later life maternal cardiovascular disease. 2011. PMID: 22131387


  47. Bonamy AK, Parikh NI, Cnattingius S, Ludvigsson JF, Ingelsson E. Birth characteristics and subsequent risks of maternal cardiovascular disease: effects of gestational age and fetal growth. 2011. PMID: 22124377


  48. Parikh NI, Cnattingius S, Dickman PW, Mittleman MA, Ludvigsson JF, Ingelsson E. Parity and risk of later-life maternal cardiovascular disease. 2010. PMID: 20152219


  49. Parikh NI, Hwang SJ, Ingelsson E, Benjamin EJ, Fox CS, Vasan RS, Murabito JM. Breastfeeding in infancy and adult cardiovascular disease risk factors. 2009. PMID: 19559168


  50. Parikh NI, Keyes MJ, Larson MG, Pou KM, Hamburg NM, Vita JA, O'Donnell CJ, Vasan RS, Mitchell GF, Hoffmann U, Fox CS, Benjamin EJ. Visceral and subcutaneous adiposity and brachial artery vasodilator function. 2009. PMID: 19282819


  51. Parikh NI, Gona P, Larson MG, Fox CS, Benjamin EJ, Murabito JM, O'Donnell CJ, Vasan RS, Levy D. Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study. 2009. PMID: 19237656


  52. Velagaleti RS, Pencina MJ, Murabito JM, Wang TJ, Parikh NI, D'Agostino RB, Levy D, Kannel WB, Vasan RS. Long-term trends in the incidence of heart failure after myocardial infarction. 2008. PMID: 18955667


  53. Parikh NI, Hwang SJ, Yang Q, Larson MG, Guo CY, Robins SJ, Sutherland P, Benjamin EJ, Levy D, Fox CS. Clinical correlates and heritability of cystatin C (from the Framingham Offspring Study). 2008. PMID: 18940290


  54. Parikh NI, Hwang SJ, Larson MG, Hoffmann U, Levy D, Meigs JB, O'Donnell CJ, Fox CS. Indexes of kidney function and coronary artery and abdominal aortic calcium (from the Framingham Offspring Study). 2008. PMID: 18678302


  55. Parikh NI, Hwang SJ, Larson MG, Levy D, Fox CS. Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study). 2008. PMID: 18572034


  56. Foster MC, Hwang SJ, Larson MG, Lichtman JH, Parikh NI, Vasan RS, Levy D, Fox CS. Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study. 2008. PMID: 18440684


  57. Parikh NI, Pencina MJ, Wang TJ, Benjamin EJ, Lanier KJ, Levy D, D'Agostino RB, Kannel WB, Vasan RS. A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study. 2008. PMID: 18195335


  58. Parikh NI, Vasan RS. Assessing the clinical utility of biomarkers in medicine. 2007. PMID: 20477384


  59. Parikh NI, Gona P, Larson MG, Wang TJ, Newton-Cheh C, Levy D, Benjamin EJ, Kannel WB, Vasan RS. Plasma renin and risk of cardiovascular disease and mortality: the Framingham Heart Study. 2007. PMID: 17895253


  60. Parikh NI, Hwang SJ, Larson MG, Cupples LA, Fox CS, Manders ES, Murabito JM, Massaro JM, Hoffmann U, O'Donnell CJ. Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts. 2007. PMID: 17785619


  61. Foster MC, Hwang SJ, Larson MG, Parikh NI, Meigs JB, Vasan RS, Wang TJ, Levy D, Fox CS. Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes. 2007. PMID: 17620532


  62. Parikh NI, Pencina MJ, Wang TJ, Lanier KJ, Fox CS, D'Agostino RB, Vasan RS. Increasing trends in incidence of overweight and obesity over 5 decades. 2007. PMID: 17349447


  63. Parikh NI, Hwang SJ, Larson MG, Meigs JB, Levy D, Fox CS. Cardiovascular disease risk factors in chronic kidney disease: overall burden and rates of treatment and control. 2006. PMID: 17000946


  64. Kuvin J, Parikh N, Salomon R, Tischler A, Daoust P, Arshanskiy Y, Coyner K, Carpino P, Pandian NG, Kimmelstiel C, Foote C, Erban J, Rastegar H. Images in cardiovascular medicine. Primary lymphoma of the heart. 2005. PMID: 15998689