Nisha Parikh, MD

Associate Professor

Clinical Interests: Dr. Parikh is a noninvasive cardiologist. She sees both men and women in her clinical practice, emphasizing primary and secondary cardiovascular disease prevention. She also has an interest in women's cardiovascular diseases across the lifespan; including cardiovascular disease in pregnancy and the post-partum period.

Research Interests: Dr. Parikh is a trained cardiovascular epidemiologist and population scientist. She demonstrated in the Multi-Ethnic Study of Atherosclerosis that the hemodynamic changes of pregnancy may not revert back to normal, may be cumulative across successive pregnancies, and can lead to left ventricular remodeling on cardiac MRI in mid-life. Along with a research team at the Framingham Heart Study, she developed a risk score for incident hypertension and this work was cited in the recent version of the US hypertension guidelines. She has added to the scientific knowledge base demonstrating which specific reproductive factors are predictors of cardiovascular disease using data from the NIH sponsored Women's Health Initiative Study and has leveraged data from the Swedish Population Registers. Her work has been supported by grants from the American Heart Association, the NIH/National Heart Lung and Blood Institute and the UCSF Preterm Birth Initiative.

Other interests: Dr. Parikh has been an active volunteer for the American Heart Association (AHA) for over ten years. She currently serves AHA Leadership Committee of the Epidemiology and Prevention Council (national level).
Education
2018 - Diversity, Equity, and Inclusion Champion Training, University of California
06/2010 - Cardiology, Harvard Beth-Israel Deaconess Medical Center
06/2007 - Cardiovascular Epidemiology, Framingham Heart Study/ Boston University School of Medicine
06/2005 - Internal Medicine Residency, Tufts New England Medical Center
MD, 06/2002 - Medicine, New York Medical College
MPH, 05/1997 - Epidemiology and Biostatistics, UC Berkeley
BA, 05/1995 - Molecular and Cellular Biology- Immunology, UC Berkeley
Publications
  1. Association of Adverse Pregnancy Outcomes With Risk of Atherosclerotic Cardiovascular Disease in Postmenopausal Women.
  2. Placental Abruption as a Risk Factor for Heart Failure.
  3. Maternal cardiovascular disease risk factors as predictors of preterm birth in California: a case-control study.
  4. Understanding Health Disparities in Cardiovascular Diseases in Pregnancy Among Black Women: Prevalence, Preventive Care, and Peripartum Support Networks
  5. Cardiovascular Disease-Related Pregnancy Complications Are Associated with Increased Maternal Levels and Trajectories of Cardiovascular Disease Biomarkers During and After Pregnancy.
  6. Impact of autoimmune rheumatic diseases on birth outcomes: a population-based study.
  7. Relation of Pregnancy Loss to Risk of Cardiovascular Disease in Parous Postmenopausal Women (From the Women's Health Initiative).
  8. Does Calculated Prognostic Estimation Lead to Different Outcomes Compared With Experience-Based Prognostication in the ICU? A Systematic Review.
  9. Contraceptive Choices in the Immediate Postpartum Period in Women With Cardiac Disease.
  10. Women's Reproductive History and Pre-Clinical Peripheral Arterial Disease in Late Life: The San Diego Population Study.
  11. Effects of reproductive period duration and number of pregnancies on midlife ECG indices: a secondary analysis from the Women's Health Initiative Clinical Trial.
  12. Association of Left Atrial Function Index with Atrial Fibrillation and Cardiovascular Disease: The Framingham Offspring Study.
  13. Reply: Hormone Status Correlates With Incidence of Heart Failure.
  14. Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study.
  15. Preeclampsia and Hypertension: Courting a Long While: Time to Make It Official.
  16. High Prevalence and Clinical/Sociodemographic Correlates of Miscarriages Among Flight Attendants.
  17. Reproductive Factors and Incidence of Heart Failure Hospitalization in the Women's Health Initiative.
  18. Harnessing the Power of Pregnancy and Pregnancy-Related Events to Predict Cardiovascular Disease in Women.
  19. Association of Pregnancy Complications and Characteristics With Future Risk of Elevated Blood Pressure: The Västerbotten Intervention Program.
  20. Reproductive history and risk of type 2 diabetes mellitus in postmenopausal women: findings from the Women's Health Initiative.
  21. Association of Left Atrial Function Index With Late Atrial Fibrillation Recurrence after Catheter Ablation.
  22. Parity, coronary heart disease and mortality in the old order Amish.
  23. Reproductive Risk Factors and Coronary Heart Disease in the Women's Health Initiative Observational Study.
  24. Racial and ethnic differences in atrial fibrillation risk factors and predictors in women: Findings from the Women's Health Initiative.
  25. HIV and coronary artery calcium score: comparison of the Hawaii Aging with HIV Cardiovascular Study and Multi-Ethnic Study of Atherosclerosis (MESA) cohorts.
  26. Association between number of live births and markers of subclinical atherosclerosis: The Dallas Heart Study.
  27. Assessment of Obesity and Cardiovascular Risk in South Asians
  28. Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens.
  29. Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort.
  30. Risk of cardiovascular disease among postmenopausal women with prior pregnancy loss: the women's health initiative.
  31. Ethnic differences in the relationship between birth weight and type 2 diabetes mellitus in postmenopausal women.
  32. Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV.
  33. Assessing differential expression in two-color microarrays: a resampling-based empirical Bayes approach.
  34. Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy.
  35. Feasibility and potential role of ferumoxytol-enhanced neuroimaging in HIV-associated neurocognitive disorder.
  36. The jugular venous pressure revisited.
  37. IL-1? enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.
  38. Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-a levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors.
  39. Rates of autonomic dysfunction in HIV patients receiving antiretroviral therapy.
  40. Albuminuria as a marker of cardiovascular risk in HIV-infected individuals receiving stable antiretroviral therapy.
  41. Methamphetamine-associated cardiomyopathy.
  42. Pregnancy Complications and the Risk of Metabolic Syndrome for the Offspring.
  43. Current Cardiovascular Risk Reports. Eds. Robinson JF and Levy D
  44. The effects of extended release niacin on lipoprotein sub-particle concentrations in HIV-infected patients.
  45. Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study.
  46. Left and codominant coronary artery circulations are associated with higher in-hospital mortality among patients undergoing percutaneous coronary intervention for acute coronary syndromes: report From the National Cardiovascular Database Cath Percutaneous
  47. Effects of antiretroviral therapy on autonomic function in early HIV infection: a preliminary report.
  48. Role of the veterans aging cohort study index in assessing total atherosclerotic burden.
  49. Association of number of live births with left ventricular structure and function. The Multi-Ethnic Study of Atherosclerosis (MESA).
  50. Subfertility and risk of later life maternal cardiovascular disease.
  51. Birth characteristics and subsequent risks of maternal cardiovascular disease: effects of gestational age and fetal growth.
  52. Sex differences in the risk of cardiovascular disease.
  53. Parity and risk of later-life maternal cardiovascular disease.
  54. Breastfeeding in infancy and adult cardiovascular disease risk factors.
  55. Visceral and subcutaneous adiposity and brachial artery vasodilator function.
  56. Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study.
  57. Long-term trends in the incidence of heart failure after myocardial infarction.
  58. Clinical correlates and heritability of cystatin C (from the Framingham Offspring Study).
  59. Indexes of kidney function and coronary artery and abdominal aortic calcium (from the Framingham Offspring Study).
  60. Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study).
  61. Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study.
  62. A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study.
  63. Assessing the clinical utility of biomarkers in medicine.
  64. Plasma renin and risk of cardiovascular disease and mortality: the Framingham Heart Study.
  65. Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts.
  66. Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes.
  67. Increasing trends in incidence of overweight and obesity over 5 decades.
  68. Cardiovascular disease risk factors in chronic kidney disease: overall burden and rates of treatment and control.
  69. Images in cardiovascular medicine. Primary lymphoma of the heart.